Data from the 2022 Census showed the number of people opting to live and work in the region has jumped 13.3pc between 2016 and 2022.
All of the major labour catchment areas in the region recorded an increase in the number of workers in the period.
The Galway city catchment area remains the largest in the region and grew by more than 25pc in the time period.
This is the equivalent of over 18,000 additional people, bringing the total to 88,253 workers in the area in 2022.
Sligo town was the second largest catchment area that year with over 24,300 resident workers. This was up 11.7pc since the previous census in 2016.
Letterkenny town labour catchment followed, according to the report. This area had 23,500 workers in 2022, rising 19pc since 2016.
This growth boosted the area into the third largest catchment in the region, moving up one spot from its position in Census 2016.
The WDC found the Roscommon town labour catchment recorded the largest overall increase in the number of workers, soaring 26.7pc from 2016 to 2022. It is now the eighth largest area, adding 1,933 new resident workers.
Ennis labour catchment recorded a lower rate of growth at just 4.4pc. The WDC attributed this slower pace of growth to the nearby areas of Shannon and Limerick and their importance as employment destinations in that region.
The most significant employment sector across the major labour catchments in the west was education, human health and social activities. This is also the largest sector across the country.
The number of workers in the region who also opted to work from home soared following the pandemic, according to census data.
Employees who said they worked mainly from home in the west of Ireland jumped 75.6pc since 2016.
The WDC also pointed to an increase in the numbers in the west who stated they worked outside the region, including in cities such as Dublin.
This could also indicate the higher incidence of working from home for the majority of the week, it said.
The WDC noted an increase in workers with a third-level education, with rates rising nationally from 56.1pc in 2016 to 63.1pc. The Galway city labour catchment area had a third level education attainment rate of 67.6pc, higher than the state average.