Where and when is it on?
The game takes place at the Aviva Stadium on Lansdowne Road in Dublin with a 5.00pm kick-off on Saturday.
Where can I watch the game?
The match is being shown on RTÉ 2. It is also being streamed live on the RTÉ Player. Plus you can follow all the action as it happens here on Independent.ie in our liveblog.
Who’s in the squads?
Ireland:
Goalkeepers: Caoimhín Kelleher (Liverpool), Mark Travers (AFC Bournemouth), Max O’Leary (Bristol City).
Defenders: Séamus Coleman (Everton), Matt Doherty (Wolverhampton Wanderers), Dara O’Shea (Ipswich Town), Nathan Collins (Brentford), Jake O’Brien (Everton), Andrew Omobamidele (Nottingham Forest), Liam Scales (Celtic), Callum O’Dowda (Cardiff City), Robbie Brady (Preston North End).
Midfielders: Will Smallbone (Southampton), Jayson Molumby (West Bromwich Albion), Alan Browne (Sunderland), Jason Knight (Bristol City), Kasey McAteer (Leicester City).
Forwards: Adam Idah (Celtic), Evan Ferguson (Brighton and Hove Albion), Sammie Szmodics (Ipswich Town), Chiedozie Ogbene (Ipswich Town), Callum Robinson (Cardiff City), Troy Parrott (AZ Alkmaar).
England:
Goalkeepers: Dean Henderson (Crystal Palace), Jordan Pickford (Everton), Nick Pope (Newcastle United).
Defenders: Trent Alexander-Arnold (Liverpool), Levi Colwill (Chelsea), Marc Guéhi (Crystal Palace), Ezri Konsa (Aston Villa), Rico Lewis (Manchester City), Tino Livramento (Newcastle), Harry Maguire (Manchester United), John Stones (Manchester City).
Midfielders: Conor Gallagher (Atlético Madrid), Morgan Gibbs-White (Nottingham Forest), Angel Gomes (Lille), Kobbie Mainoo (Manchester United), Declan Rice (Arsenal).
Forwards; Jarrod Bowen (West Ham United), Eberechi Eze (Crystal Palace), Anthony Gordon (Newcastle United), Jack Grealish (Manchester City), Harry Kane (Bayern Munich), Noni Madueke (Chelsea), Bukayo Saka (Arsenal).
What can I read about and watch on Independent.ie?
It’s a first game in charge for Heimir Hallgrimsson and Aidan Fitzmaurice has the latest from the new Ireland boss below. Aidan has also looked at previous Dublin clashes between the two sides while Daniel McDonnell explains just why the Nations League is so important for Ireland.
Finally, Sean O’Connor has this video preview for you.
Ireland v England preview
What are the odds?
England are odds-on favourites at 2/5 with Ireland 11/2 and the draw is 3/1.