Greene had given Ireland a solid start, handing the baton to Adeleke in fourth place.
The 21-year-old ran an astonishing leg as she left Dutch world and European relay champion Lieke Klaver in her wake, bringing Ireland back on level terms with the United States.
Although only a relay split, a time of 48.45secs would have been good enough to win the Olympic silver medal in Tokyo and on this form Adeleke must be considered a medal chance at both next month’s European Championships in Rome and then the Olympics in Paris.
Barr held his own on the third leg although the USA opened the gap further, but Mawdsley took the baton just ahead of Bol with Nigeria in the mix for the medals as well.
There would be no catching Kendall Ellis of the USA, but Mawdsley was not prepared to be intimidated by Bol, the world 400m hurdles and 4x400m champion.
She pushed Bol all the way to the line with the Dutch athlete just edging out Mawdsley for second place.